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Muscle As we age, our muscles generally decrease in strength, endurance,
size and weight. Typically, we lose about 23 percent of our muscle mass
by age 80 as both the number and size of muscle fibers decrease. These
changes may be more the result of inactivity, poor nutrition, and chronic
illness or disease than the result of age per se. Much of this decrease
in muscle mass can be prevented by maintaining physical fitness.
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